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　　三九養(yǎng)生堂記者 鄧肯·蓋伊 報道

精彩|　　中??(zhong)新??(xin)網(wǎng)秘(wang)北??(bei)京?(jing)10月?(yue)19日??(ri)電??(dian) (記??(ji)者?(zhe) 孫??(sun)自??(zi)法??(fa))近??(jin)年??(nian)來??(lai)?，隨?(sui)著??(zhe)基??(ji)因??(yin)測??(ce)序??(xu)技??(ji)術??(shu)和?(he)算??(suan)法??(fa)不??(bu)斷??(duan)發(fā)??(fa)展??(zhan)?，大??(da)量??(liang)物??(wu)種??(zhong)基??(ji)因??(yin)組??(zu)被??(bei)陸??(lu)續(xù)??(xu)測?(ce)序??(xu)和??(he)組??(zu)裝??(zhuang)?，為??(wei)相??(xiang)關??(guan)研??(yan)究??(jiu)和??(he)應??(ying)用??(yong)提??(ti)供??(gong)重??(zhong)要??(yao)遺??(yi)傳??(chuan)信??(xin)息??(xi)??。??因??(yin)此??(ci)?，如??(ru)何??(he)精祝(jing)準??(zhun)檢??(jian)測??(ce)評??(ping)估?(gu)基??(ji)因?(yin)組??(zu)組??(zu)裝??(zhuang)質??(zhi)量??(liang)高??(gao)低??(di)、避??(bi)免??(mian)組??(zu)裝??(zhuang)錯??(cuo)誤??(wu)等??(deng)非?(fei)常?(chang)關?(guan)鍵??(jian)?，也??(ye)備??(bei)受??(shou)關??(guan)注??(zhu)??。　　針??(zhen)對??(dui)這??(zhe)一?(yi)問??(wen)題??(ti)??，該??(gai)研??(yan)究??(jiu)團??(tuan)隊??(dui)研??(yan)發(fā)??(fa)的??(de)CRAQ通??(tong)過??(guo)將??(jiang)原??(yuan)始??(shi)測??(ce)序??(xu)序??(xu)列??(lie)比??(bi)對??(dui)到??(dao)組??(zu)裝??(zhuang)的??(de)基??(ji)因??(yin)組??(zu)上??(shang)??，基??(ji)于??(yu)序??(xu)列?(lie)比??(bi)對??(dui)產(chǎn)??(chan)生??(sheng)的?(de)有??(you)效??(xiao)“剪??(jian)切??(qie)對??(dui)齊?(qi)”信??(xin)息??(xi)??，可??(ke)精??(jing)準??(zhun)地??(di)檢??(jian)測??(ce)基??(ji)因?(yin)組??(zu)中??(zhong)存??(cun)在??(zai)的?(de)組??(zu)裝??(zhuang)錯?(cuo)誤??(wu)??。??結??(jie)合??(he)長??(chang)讀??(du)長??(chang)測??(ce)序??(xu)片??(pian)段??(duan)和??(he)短??(duan)讀??(du)長??(chang)測??(ce)序??(xu)片??(pian)段??(duan)與??(yu)基??(ji)因??(yin)組??(zu)比??(bi)對?(dui)的??(de)特?(te)征??(zheng)??，CRAQ可??(ke)以??(yi)識??(shi)別??(bie)基??(ji)因??(yin)組??(zu)內(nèi)?(nei)小??(xiao)規(guī)??(gui)模??(mo)的??(de)區(qū)??(qu)域??(yu)組??(zu)裝??(zhuang)錯??(cuo)誤??(wu)和??(he)大??(da)范??(fan)圍??(wei)的??(de)結??(jie)構??(gou)組??(zu)裝??(zhuang)錯??(cuo)誤??(wu)??，不??(bu)同??(tong)類?(lei)別??(bie)的??(de)錯??(cuo)誤??(wu)數(shù)?(shu)量??(liang)經(jīng)??(jing)過??(guo)統(tǒng)??(tong)計??(ji)和??(he)標??(biao)準??(zhun)化??(hua)處??(chu)理??(li)后??(hou)被?(bei)轉?(zhuan)化??(hua)為?(wei)兩??(liang)個??(ge)組??(zu)裝??(zhuang)質??(zhi)量?(liang)評??(ping)估??(gu)指??(zhi)標??(biao)??，以??(yi)反??(fan)映??(ying)不??(bu)同??(tong)層??(ceng)面??(mian)的??(de)基?(ji)因?(yin)組?(zu)組??(zu)裝??(zhuang)質??(zhi)量??(liang)??。

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