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學(xué)習(xí)快評丨qibao666888　　非??(fei)編??(bian)碼??(ma)RNA??，尤??(you)其?(qi)是??(shi)長??(chang)鏈??(lian)非??(fei)編??(bian)碼??(ma)RNA在?(zai)哺?(bu)乳??(ru)動(dòng)??(dong)物?(wu)大??(da)腦??(nao)的??(de)發(fā)??(fa)育??(yu)、成??(cheng)熟??(shu)和??(he)疾??(ji)病??(bing)中??(zhong)發(fā)??(fa)揮??(hui)著??(zhe)重??(zhong)要??(yao)作??(zuo)用??(yong)??。??作??(zuo)為??(wei)此??(ci)次??(ci)的??(de)研?(yan)究??(jiu)亮??(liang)點(diǎn)??(dian)之??(zhi)一??(yi)??，團(tuán)??(tuan)隊(duì)??(dui)首?(shou)次??(ci)整??(zheng)合??(he)了?(le)長??(chang)鏈??(lian)非??(fei)編??(bian)碼??(ma)RNA的??(de)空??(kong)間??(jian)表??(biao)達(dá)?(da)數(shù)??(shu)據(jù)??(ju)??，發(fā)??(fa)現(xiàn)??(xian)長??(chang)鏈??(lian)非??(fei)編??(bian)碼??(ma)RNA的??(de)表??(biao)達(dá)??(da)在??(zai)成??(cheng)年??(nian)小??(xiao)鼠??(shu)大??(da)腦?(nao)中??(zhong)具??(ju)有??(you)區(qū)??(qu)域??(yu)選??(xuan)擇?(ze)性??(xing)??，在??(zai)發(fā)??(fa)育??(yu)中??(zhong)的??(de)小??(xiao)鼠??(shu)大??(da)腦??(nao)內(nèi)??(nei)則??(ze)呈??(cheng)現(xiàn)??(xian)出??(chu)時(shí)??(shi)空??(kong)動(dòng)??(dong)態(tài)??(tai)性??(xing)??，為??(wei)神??(shen)經(jīng)??(jing)功??(gong)能?(neng)與??(yu)非??(fei)編??(bian)碼?(ma)RNA相??(xiang)關(guān)??(guan)性??(xing)的?(de)研??(yan)究??(jiu)奠?(dian)定??(ding)了??(le)基??(ji)礎(chǔ)??(chu)??。(完??(wan))　　通??(tong)過??(guo)單??(dan)細(xì)??(xi)胞??(bao)分??(fen)辨?(bian)率??(lv)和??(he)全??(quan)基??(ji)因??(yin)組??(zu)覆??(fu)蓋??(gai)的??(de)轉(zhuǎn)??(zhuan)錄??(lu)組??(zu)數(shù)??(shu)據(jù)??(ju)?，科?(ke)研??(yan)人??(ren)員??(yuan)成??(cheng)功??(gong)識(shí)??(shi)別??(bie)了??(le)具??(ju)有??(you)不??(bu)同??(tong)空??(kong)間??(jian)分??(fen)布??(bu)特??(te)征??(zheng)的??(de)神??(shen)經(jīng)??(jing)元??(yuan)亞秘(ya)型??(xing)??。??例??(li)如??(ru)?，研??(yan)究??(jiu)揭??(jie)示??(shi)了??(le)不??(bu)同??(tong)腦??(nao)干??(gan)運(yùn)??(yun)動(dòng)?(dong)核??(he)團(tuán)??(tuan)中??(zhong)不??(bu)同??(tong)類??(lei)型??(xing)的??(de)運(yùn)??(yun)動(dòng)??(dong)神?(shen)經(jīng)??(jing)元??(yuan)亞?(ya)型??(xing)?，這??(zhe)一??(yi)發(fā)??(fa)現(xiàn)??(xian)為?(wei)深??(shen)入?(ru)解??(jie)析?(xi)運(yùn)?(yun)動(dòng)??(dong)控??(kong)制??(zhi)的??(de)分??(fen)子??(zi)機(jī)??(ji)制??(zhi)提??(ti)供??(gong)了??(le)關(guān)??(guan)鍵??(jian)線??(xian)索??(suo)??。研??(yan)究??(jiu)還??(hai)發(fā)?(fa)現(xiàn)??(xian)部??(bu)分??(fen)非??(fei)神??(shen)經(jīng)?(jing)元??(yuan)細(xì)??(xi)胞?(bao)類??(lei)型??(xing)表??(biao)現(xiàn)??(xian)出??(chu)區(qū)??(qu)域??(yu)富??(fu)集??(ji)特??(te)征??(zheng)?，進(jìn)?(jin)一??(yi)步??(bu)拓??(tuo)展??(zhan)了??(le)對??(dui)大??(da)腦??(nao)細(xì)??(xi)胞??(bao)分??(fen)布??(bu)及??(ji)其??(qi)功??(gong)能??(neng)多??(duo)樣??(yang)性??(xing)的??(de)認(rèn)??(ren)知??(zhi)??。。