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　　三九養(yǎng)生堂記者 鄧肯·蓋伊 報道

精彩|　　2022年??(nian)12月??(yue)??，復(fù)??(fu)旦??(dan)大??(da)學(xué)??(xue)附??(fu)屬??(shu)眼?(yan)耳??(er)鼻??(bi)喉??(hou)科??(ke)醫(yī)??(yi)院??(yuan)耳??(er)聾??(long)基??(ji)因??(yin)治??(zhi)療?(liao)團(tuán)??(tuan)隊(duì)?(dui)對??(dui)一??(yi)名??(ming)患??(huan)兒??(er)進(jìn)??(jin)行??(xing)了??(le)全??(quan)球??(qiu)首??(shou)例??(li)遺??(yi)傳??(chuan)性??(xing)耳??(er)聾??(long)基??(ji)因??(yin)治?(zhi)療??(liao)藥?(yao)物??(wu)注??(zhu)射??(she)??。??該??(gai)項(xiàng)??(xiang)基??(ji)因??(yin)治??(zhi)療??(liao)藥??(yao)物??(wu)技??(ji)術(shù)??(shu)??，開??(kai)辟??(pi)了??(le)先??(xian)天??(tian)性??(xing)耳?(er)聾??(long)治??(zhi)療?(liao)的??(de)新?(xin)方??(fang)向??(xiang)??。包??(bao)括??(kuo)該?(gai)患??(huan)兒??(er)在??(zai)內(nèi)??(nei)??，該?(gai)院??(yuan)進(jìn)??(jin)行??(xing)的??(de)全??(quan)球??(qiu)首??(shou)批??(pi)多??(duo)例??(li)基??(ji)因??(yin)治??(zhi)療??(liao)臨??(lin)床??(chuang)試??(shi)驗(yàn)??(yan)已??(yi)被??(bei)歐??(ou)洲??(zhou)基??(ji)因??(yin)和??(he)細(xì)??(xi)胞??(bao)治??(zhi)療?(liao)學(xué)??(xue)會??(hui)年??(nian)會??(hui)(簡??(jian)稱??(cheng)ESGCT年??(nian)會??(hui))正??(zheng)式??(shi)接??(jie)收??(shou)為??(wei)大??(da)會??(hui)報??(bao)告??(gao)??，并??(bing)將??(jiang)在??(zai)比??(bi)利??(li)時??(shi)布??(bu)魯?(lu)塞?(sai)爾??(er)舉??(ju)行??(xing)的??(de)第?(di)30屆??(jie)ESGCT大??(da)會??(hui)上??(shang)向??(xiang)全??(quan)球??(qiu)同??(tong)行?(xing)分??(fen)享??(xiang)???！　?fù)??(fu)旦?(dan)大??(da)學(xué)??(xue)附??(fu)屬?(shu)眼??(yan)耳??(er)鼻??(bi)喉??(hou)科??(ke)醫(yī)??(yi)院??(yuan)耳??(er)聾??(long)基??(ji)因??(yin)治?(zhi)療??(liao)團(tuán)??(tuan)隊(duì)?(dui)采??(cai)用??(yong)基??(ji)因??(yin)補(bǔ)??(bu)償??(chang)的?(de)方??(fang)式??(shi)??，將??(jiang)基??(ji)因??(yin)治??(zhi)療??(liao)藥??(yao)物??(wu)通??(tong)過??(guo)微??(wei)創(chuàng)??(chuang)局??(ju)部??(bu)注??(zhu)射??(she)到??(dao)患??(huan)兒?(er)內(nèi)?(nei)耳??(er)??，彌??(mi)補(bǔ)??(bu)缺??(que)陷??(xian)的??(de)耳??(er)畸??(ji)蛋??(dan)白??(bai)??，從??(cong)而??(er)恢??(hui)復(fù)?(fu)或??(huo)改??(gai)善??(shan)OTOF突??(tu)變?(bian)耳??(er)聾??(long)患??(huan)兒??(er)的??(de)聽??(ting)覺??(jiao)和??(he)言??(yan)語??(yu)功??(gong)能??(neng)??。?目??(mu)前?(qian)??，該??(gai)團(tuán)??(tuan)隊(duì)?(dui)已?(yi)納??(na)入??(ru)多??(duo)例??(li)患??(huan)兒??(er)??，臨??(lin)床??(chuang)試??(shi)驗(yàn)??(yan)結(jié)??(jie)果??(guo)表??(biao)明??(ming)??，內(nèi)??(nei)耳??(er)基??(ji)因??(yin)治?(zhi)療??(liao)策??(ce)略??(lve)在??(zai)耳??(er)聾?(long)患??(huan)者??(zhe)中??(zhong)是??(shi)安??(an)全??(quan)、有??(you)效??(xiao)的??(de)??。該??(gai)研??(yan)究??(jiu)為??(wei)OTOF基??(ji)因??(yin)突??(tu)變??(bian)致??(zhi)聾??(long)患??(huan)者??(zhe)提??(ti)供??(gong)了??(le)特??(te)異??(yi)性??(xing)的??(de)基??(ji)因??(yin)治??(zhi)療??(liao)候??(hou)選??(xuan)藥??(yao)物??(wu)??，是?(shi)遺??(yi)傳?(chuan)性??(xing)耳??(er)聾?(long)治??(zhi)療??(liao)領(lǐng)??(ling)域??(yu)的??(de)重??(zhong)要??(yao)突??(tu)破??(po)??。與??(yu)此??(ci)同??(tong)時??(shi)??，在??(zai)術(shù)??(shu)前??(qian)評??(ping)估??(gu)、給??(gei)藥??(yao)方?(fang)式?(shi)、術(shù)??(shu)中??(zhong)監(jiān)??(jian)控??(kong)、術(shù)??(shu)后??(hou)護(hù)??(hu)理??(li)等??(deng)方??(fang)面??(mian)??，該?(gai)團(tuán)??(tuan)隊(duì)?(dui)建?(jian)立??(li)了??(le)成??(cheng)熟??(shu)的??(de)臨??(lin)床??(chuang)治??(zhi)療??(liao)方??(fang)案??(an)??，為??(wei)后??(hou)續(xù)?(xu)研??(yan)究??(jiu)及??(ji)臨??(lin)床??(chuang)應(yīng)??(ying)用??(yong)提??(ti)供??(gong)有??(you)力??(li)支?(zhi)撐??(cheng)??。

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