三九養(yǎng)生堂記者 鄧肯·蓋伊 報道
精彩| 據(jù)??(ju)美??(mei)國??(guo)《連??(lian)線??(xian)》雜??(za)志??(zhi)報??(bao)道??(dao)??，在??(zai)“腦??(nao)計??(ji)劃??(hua)”的??(de)早?(zao)期??(qi)階??(jie)段??(duan)??，科??(ke)學??(xue)家??(jia)開??(kai)發(fā)??(fa)了??(le)創(chuàng)??(chuang)建??(jian)小??(xiao)鼠??(shu)大?(da)腦??(nao)細??(xi)胞??(bao)圖?(tu)譜??(pu)的??(de)方??(fang)法??(fa)??，但??(dan)將??(jiang)所?(suo)用??(yong)技??(ji)術(shù)??(shu)引?(yin)入??(ru)對??(dui)人??(ren)類??(lei)大??(da)腦??(nao)的??(de)研??(yan)究??(jiu)并??(bing)非?(fei)易??(yi)事??(shi)??。??中??(zhong)國??(guo)科??(ke)學??(xue)院??(yuan)腦??(nao)科??(ke)學??(xue)與??(yu)智??(zhi)能??(neng)技?(ji)術(shù)??(shu)卓??(zhuo)越??(yue)創(chuàng)??(chuang)新??(xin)中??(zhong)心??(xin)青??(qing)年?(nian)研??(yan)究??(jiu)員??(yuan)孫??(sun)怡??(yi)迪??(di)告??(gao)訴??(su)科??(ke)技??(ji)日??(ri)報??(bao)記?(ji)者??(zhe)??，此?(ci)前??(qian)??，識??(shi)別??(bie)腦??(nao)細??(xi)胞??(bao)亞??(ya)型??(xing)的??(de)單??(dan)細??(xi)胞??(bao)測??(ce)序??(xu)技??(ji)術(shù)??(shu)一??(yi)般??(ban)用??(yong)于??(yu)小??(xiao)鼠??(shu)等?(deng)實??(shi)驗??(yan)動??(dong)物??(wu)??，這?(zhe)是??(shi)因??(yin)為?(wei)它??(ta)對??(dui)取??(qu)樣?(yang)細??(xi)胞??(bao)的??(de)活??(huo)性??(xing)和??(he)質(zhì)??(zhi)量??(liang)要??(yao)求??(qiu)極??(ji)高?(gao)??，而??(er)人??(ren)腦??(nao)樣??(yang)本??(ben)只??(zhi)能祝(neng)來??(lai)自??(zi)已??(yi)故??(gu)的??(de)捐??(juan)贈??(zeng)者?(zhe)或??(huo)腦??(nao)手??(shou)術(shù)??(shu)患??(huan)者??(zhe)??，這??(zhe)些??(xie)樣??(yang)本??(ben)的??(de)新??(xin)鮮?(xian)度??(du)和??(he)數(shù)??(shu)量??(liang)有??(you)限??(xian)??。因??(yin)此??(ci)對??(dui)科??(ke)學??(xue)家??(jia)而??(er)言??(yan)??，使??(shi)用??(yong)單?(dan)細??(xi)胞??(bao)測??(ce)序??(xu)技??(ji)術(shù)??(shu)分??(fen)析??(xi)人??(ren)腦??(nao)是??(shi)一??(yi)個??(ge)挑??(tiao)戰(zhàn)??(zhan)??。同??(tong)時?(shi)??，人??(ren)腦??(nao)組??(zu)織??(zhi)在??(zai)取??(qu)樣??(yang)和??(he)處??(chu)理??(li)過??(guo)程??(cheng)中??(zhong)可??(ke)能??(neng)會??(hui)受??(shou)到??(dao)更??(geng)多??(duo)損?(sun)傷?(shang)??，或??(huo)將??(jiang)影??(ying)響??(xiang)結(jié)??(jie)果??(guo)的??(de)準??(zhun)確??(que)性?(xing)??。 深??(shen)圳??(zhen)華??(hua)大??(da)生??(sheng)命??(ming)科??(ke)學??(xue)研??(yan)究??(jiu)院??(yuan)腦??(nao)科??(ke)學??(xue)主??(zhu)任??(ren)科??(ke)學??(xue)家??(jia)、研?(yan)究??(jiu)員??(yuan)劉??(liu)石??(shi)平??(ping)告??(gao)訴?(su)記??(ji)者??(zhe)??，細?(xi)胞??(bao)的??(de)功??(gong)能??(neng)是??(shi)由??(you)細??(xi)胞??(bao)內(nèi)?(nei)部??(bu)不??(bu)同??(tong)層??(ceng)面??(mian)的?(de)信??(xin)息??(xi)以??(yi)及??(ji)它??(ta)所??(suo)處??(chu)的??(de)微??(wei)環(huán)??(huan)境??(jing)共??(gong)同??(tong)決??(jue)定??(ding)的??(de)??，而??(er)細??(xi)胞??(bao)內(nèi)??(nei)部?(bu)不??(bu)同??(tong)層?(ceng)面??(mian)的?(de)信??(xin)息??(xi)包??(bao)括??(kuo)了??(le)DNA序??(xu)列??(lie)結(jié)??(jie)構(gòu)??(gou)、DNA表??(biao)觀??(guan)結(jié)??(jie)構(gòu)??(gou)、基??(ji)因??(yin)轉(zhuǎn)??(zhuan)錄?(lu)組??(zu)的??(de)表?(biao)達??(da)、蛋??(dan)白??(bai)的??(de)表??(biao)達??(da)等??(deng)等??(deng)??。??因??(yin)此??(ci)??，上??(shang)述??(shu)兩??(liang)種?(zhong)信??(xin)息??(xi)是?(shi)決??(jue)定??(ding)細??(xi)胞??(bao)功??(gong)能??(neng)的??(de)核?(he)心??(xin)信?(xin)息??(xi)之??(zhi)一??(yi)??，對??(dui)于?(yu)繪??(hui)制??(zhi)腦??(nao)圖??(tu)譜??(pu)至??(zhi)關(guān)??(guan)重??(zhong)要??(yao)??。
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責編：呂程平