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學(xué)習(xí)快評丨qibao666888　　北??(bei)京??(jing)時(shí)??(shi)間??(jian)3月??(yue)25日?(ri)??，清?(qing)華??(hua)大??(da)學(xué)??(xue)藥??(yao)學(xué)??(xue)院??(yuan)丁??(ding)勝??(sheng)教??(jiao)授??(shou)團(tuán)??(tuan)隊(duì)??(dui)在??(zai)國??(guo)際??(ji)頂??(ding)級??(ji)學(xué)??(xue)術(shù)??(shu)期??(qi)刊??(kan)《Immunity》發(fā)??(fa)表??(biao)突??(tu)破?(po)性??(xing)研??(yan)究?(jiu)??，首?(shou)次?(ci)揭??(jie)示??(shi)控??(kong)制??(zhi)小??(xiao)膠??(jiao)質(zhì)?(zhi)細(xì)??(xi)胞??(bao)“加??(jia)速??(su)—控??(kong)速??(su)”平??(ping)衡??(heng)的??(de)關(guān)??(guan)鍵??(jian)開??(kai)關(guān)??(guan)??，并??(bing)成??(cheng)功??(gong)從??(cong)2400多??(duo)種??(zhong)化??(hua)合??(he)物?(wu)中??(zhong)篩??(shai)選??(xuan)出??(chu)能??(neng)精??(jing)準(zhǔn)??(zhun)修??(xiu)復(fù)??(fu)該??(gai)系??(xi)統(tǒng)??(tong)的??(de)藥??(yao)物?(wu)小??(xiao)分??(fen)子??(zi)BMS265246??。??在??(zai)動(dòng)??(dong)物??(wu)實(shí)??(shi)驗(yàn)??(yan)中??(zhong)??，這??(zhe)種??(zhong)新??(xin)型?(xing)CDK2抑??(yi)制??(zhi)劑??(ji)使??(shi)患??(huan)病??(bing)小??(xiao)鼠??(shu)的??(de)腦??(nao)部??(bu)炎??(yan)癥??(zheng)消??(xiao)退??(tui)??，社??(she)交??(jiao)和??(he)記?(ji)憶??(yi)功?(gong)能??(neng)基?(ji)本??(ben)恢??(hui)復(fù)??(fu)正??(zheng)常??(chang)??。這??(zhe)項(xiàng)??(xiang)發(fā)??(fa)現(xiàn)??(xian)不?(bu)僅??(jin)為??(wei)學(xué)??(xue)界??(jie)深??(shen)入??(ru)理?(li)解??(jie)細(xì)??(xi)胞??(bao)周??(zhou)期??(qi)蛋??(dan)白??(bai)調(diào)秘(tiao)控??(kong)非??(fei)分??(fen)裂??(lie)細(xì)??(xi)胞??(bao)功??(gong)能??(neng)提??(ti)供??(gong)了??(le)嶄??(zhan)新??(xin)的??(de)實(shí)??(shi)例??(li)??，更??(geng)為??(wei)治??(zhi)療??(liao)十??(shi)多??(duo)種??(zhong)神??(shen)經(jīng)??(jing)疾?(ji)病??(bing)提??(ti)供??(gong)了??(le)全??(quan)新?(xin)路?(lu)徑??(jing)???！　　跋??(xiang)象??(xiang)一?(yi)下?(xia)??，如?(ru)果??(guo)自??(zi)動(dòng)??(dong)駕??(jia)駛??(shi)中??(zhong)的??(de)汽?(qi)車??(che)控??(kong)速??(su)系??(xi)統(tǒng)??(tong)失??(shi)靈??(ling)??，加??(jia)速??(su)時(shí)?(shi)會(huì)??(hui)發(fā)??(fa)生??(sheng)什??(shen)么??(me)？??”丁??(ding)勝??(sheng)用??(yong)比??(bi)喻??(yu)解??(jie)釋??(shi)團(tuán)??(tuan)隊(duì)??(dui)的??(de)發(fā)??(fa)現(xiàn)??(xian)??，“MEF2C基?(ji)因??(yin)就?(jiu)是?(shi)小??(xiao)膠??(jiao)質(zhì)??(zhi)細(xì)??(xi)胞??(bao)行??(xing)駛??(shi)速?(su)度??(du)控??(kong)制??(zhi)的??(de)核??(he)心??(xin)元??(yuan)件??(jian)之?(zhi)一?(yi)??，它??(ta)通??(tong)過??(guo)一??(yi)套??(tao)精?(jing)密??(mi)的??(de)蛋??(dan)白?(bai)質(zhì)??(zhi)控??(kong)制??(zhi)系??(xi)統(tǒng)??(tong)維??(wei)持??(chi)免??(mian)疫??(yi)平??(ping)衡??(heng)??。??”。