三九養(yǎng)生堂記者 鄧肯·蓋伊 報(bào)道
精彩| 胡??(hu)海??(hai)嵐??(lan)介??(jie)紹??(shao)??，這??(zhe)項(xiàng)??(xiang)基??(ji)于??(yu)藥??(yao)代?(dai)動(dòng)??(dong)力??(li)學(xué)??(xue)和??(he)藥??(yao)效??(xiao)學(xué)??(xue)的??(de)研??(yan)究??(jiu)揭??(jie)示??(shi)了?(le)氯??(lv)胺?(an)酮??(tong)獨(dú)??(du)特??(te)的??(de)藥??(yao)化?(hua)特??(te)征??(zheng)??，不??(bu)但??(dan)為??(wei)臨?(lin)床?(chuang)上??(shang)實(shí)??(shi)現(xiàn)??(xian)更??(geng)低??(di)劑??(ji)量??(liang)用??(yong)藥??(yao)、更??(geng)持??(chi)久??(jiu)療??(liao)效??(xiao)提??(ti)供??(gong)了??(le)理??(li)論??(lun)指??(zhi)導(dǎo)??(dao)??，也??(ye)將??(jiang)對(duì)??(dui)新??(xin)型??(xing)抗??(kang)抑??(yi)郁??(yu)藥??(yao)物?(wu)的??(de)改?(gai)造??(zao)提??(ti)供?(gong)方??(fang)向??(xiang)和??(he)依??(yi)據(jù)??(ju)??。??“未??(wei)來??(lai)我??(wo)們??(men)也??(ye)許??(xu)能??(neng)通??(tong)過?(guo)調(diào)??(tiao)控??(kong)氯??(lv)胺?(an)酮??(tong)‘卡??(ka)’在??(zai)受??(shou)體??(ti)里??(li)的??(de)時(shí)?(shi)間??(jian)??，來??(lai)延??(yan)長??(chang)氯??(lv)胺??(an)酮??(tong)的??(de)藥??(yao)效??(xiao)??，進(jìn)??(jin)而??(er)減??(jian)少??(shao)重??(zhong)復(fù)??(fu)給?(gei)藥?(yao)??。”(完?(wan)) “我??(wo)們??(men)發(fā)??(fa)現(xiàn)??(xian)??，實(shí)??(shi)驗(yàn)??(yan)小??(xiao)鼠??(shu)注??(zhu)射??(she)1小??(xiao)時(shí)??(shi)后??(hou)??，氯??(lv)胺??(an)酮??(tong)對(duì)??(dui)外??(wai)側(cè)??(ce)韁??(jiang)核??(he)中??(zhong)的??(de)NMDA受??(shou)體??(ti)電??(dian)流??(liu)有??(you)80%的??(de)抑??(yi)制??(zhi)??。?有??(you)點(diǎn)??(dian)出??(chu)乎??(hu)意?(yi)料?(liao)的??(de)是??(shi)??，在??(zai)注??(zhu)射??(she)24小??(xiao)時(shí)??(shi)后??(hou)??，仍?(reng)然??(ran)存??(cun)在??(zai)50%左??(zuo)右??(you)的??(de)抑??(yi)制??(zhi)??。”胡??(hu)海??(hai)嵐??(lan)說??(shuo)??。
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