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學習快評丨qibao666888　　蛋??(dan)白??(bai)質(zhì)??(zhi)是?(shi)由??(you)氨??(an)基??(ji)酸??(suan)序??(xu)列?(lie)構(gòu)??(gou)成??(cheng)的??(de)??，氨?(an)基?(ji)酸??(suan)序??(xu)列??(lie)的??(de)長?(chang)度??(du)從??(cong)數(shù)??(shu)百??(bai)個??(ge)到??(dao)上??(shang)千??(qian)個?(ge)不??(bu)等??(deng)??。??AI時??(shi)代??(dai)??，數(shù)??(shu)據(jù)?(ju)是?(shi)推??(tui)動??(dong)技??(ji)術(shù)??(shu)進??(jin)步??(bu)的??(de)核??(he)心??(xin)資??(zi)源??(yuan)??，龐??(pang)大??(da)的??(de)蛋??(dan)白?(bai)質(zhì)?(zhi)序??(xu)列?(lie)數(shù)??(shu)據(jù)??(ju)集??(ji)能??(neng)幫??(bang)助?(zhu)模?(mo)型??(xing)更??(geng)好??(hao)地??(di)理??(li)解??(jie)蛋??(dan)白?(bai)質(zhì)??(zhi)的??(de)序??(xu)列??(lie)、結(jié)??(jie)構(gòu)??(gou)和??(he)功??(gong)能??(neng)關(guān)??(guan)系??(xi)??。洪??(hong)亮??(liang)團??(tuan)隊??(dui)建??(jian)立??(li)的??(de)蛋??(dan)白??(bai)質(zhì)??(zhi)序??(xu)列??(lie)數(shù)??(shu)據(jù)??(ju)集??(ji)Venus-Pod(Venus-Protein Outsize Dataset)含??(han)有??(you)近??(jin)90億??(yi)條??(tiao)蛋??(dan)白??(bai)質(zhì)??(zhi)序??(xu)列??(lie)??，包??(bao)含??(han)數(shù)??(shu)億??(yi)個??(ge)功??(gong)能??(neng)標??(biao)簽??(qian)??，是??(shi)全??(quan)球??(qiu)數(shù)??(shu)據(jù)??(ju)規(guī)??(gui)模??(mo)最??(zui)大??(da)、功??(gong)能?(neng)批??(pi)注??(zhu)標??(biao)簽??(qian)最??(zui)多??(duo)的??(de)數(shù)??(shu)據(jù)??(ju)集??(ji)??，也??(ye)是?(shi)另?(ling)一??(yi)行??(xing)業(yè)??(ye)知??(zhi)名??(ming)模??(mo)型??(xing)——美??(mei)國??(guo)ESM-C模??(mo)型??(xing)訓(xùn)??(xun)練??(lian)用??(yong)的?(de)21億??(yi)蛋??(dan)白??(bai)質(zhì)??(zhi)序??(xu)列??(lie)的??(de)4倍??(bei)體??(ti)量??(liang)??。　　蛋??(dan)白??(bai)質(zhì)??(zhi)是??(shi)由??(you)20種??(zhong)氨??(an)基??(ji)酸??(suan)組?(zu)成??(cheng)的??(de)一??(yi)條??(tiao)高??(gao)分??(fen)子??(zi)鏈??(lian)??，這??(zhe)個??(ge)高??(gao)分??(fen)子??(zi)鏈?(lian)會??(hui)扭??(niu)曲??(qu)并??(bing)折??(zhe)疊??(die)成??(cheng)獨??(du)特??(te)的??(de)三??(san)維??(wei)結(jié)??(jie)構(gòu)??(gou)??，正??(zheng)是??(shi)這??(zhe)種??(zhong)獨??(du)特??(te)結(jié)??(jie)構(gòu)??(gou)賦??(fu)予??(yu)了??(le)特??(te)定??(ding)蛋??(dan)白??(bai)質(zhì)??(zhi)的??(de)生??(sheng)物??(wu)功??(gong)能?(neng)??。??要??(yao)設(shè)??(she)計?(ji)出??(chu)一??(yi)款??(kuan)成??(cheng)功??(gong)的?(de)蛋?(dan)白??(bai)質(zhì)??(zhi)產(chǎn)??(chan)品??(pin)??，不??(bu)能??(neng)只??(zhi)關(guān)??(guan)注??(zhu)它?(ta)的??(de)三??(san)維??(wei)結(jié)??(jie)構(gòu)??(gou)??，而??(er)是??(shi)要??(yao)能??(neng)成?(cheng)功??(gong)預(yù)??(yu)測??(ce)和??(he)設(shè)??(she)計??(ji)它??(ta)的??(de)功??(gong)能??(neng)??。洪??(hong)亮??(liang)團??(tuan)隊?(dui)直??(zhi)接??(jie)瞄??(miao)準??(zhun)“功??(gong)能?(neng)預(yù)??(yu)測??(ce)”這??(zhe)一??(yi)終??(zhong)極??(ji)目??(mu)標??(biao)??，將??(jiang)復(fù)??(fu)雜??(za)的??(de)蛋??(dan)白??(bai)質(zhì)??(zhi)設(shè)??(she)計??(ji)變??(bian)成??(cheng)以??(yi)需?(xu)求??(qiu)為??(wei)導(dǎo)??(dao)向??(xiang)??，配??(pei)合??(he)少??(shao)量??(liang)實??(shi)驗??(yan)輸??(shu)出??(chu)結(jié)??(jie)果??(guo)的??(de)簡?(jian)單??(dan)過??(guo)程?(cheng)??。。