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學(xué)習(xí)快評(píng)丨qibao666888　　此??(ci)次??(ci)研??(yan)究??(jiu)覆??(fu)蓋??(gai)從??(cong)小??(xiao)鼠?(shu)胚??(pei)胎?(tai)期??(qi)到??(dao)成??(cheng)年??(nian)期??(qi)7個(gè)?(ge)不??(bu)同??(tong)時(shí)??(shi)間??(jian)點(diǎn)??(dian)的?(de)腦??(nao)部??(bu)全??(quan)發(fā)??(fa)育??(yu)階??(jie)段??(duan)數(shù)??(shu)據(jù)??(ju)?，揭??(jie)示??(shi)了??(le)411個(gè)??(ge)具??(ju)有??(you)顯??(xian)著??(zhu)時(shí)??(shi)空??(kong)動(dòng)??(dong)態(tài)?(tai)變??(bian)化??(hua)的??(de)轉(zhuǎn)??(zhuan)錄??(lu)因??(yin)子??(zi)?，不??(bu)僅?(jin)為??(wei)大??(da)腦??(nao)發(fā)??(fa)育??(yu)研??(yan)究??(jiu)提??(ti)供??(gong)了??(le)全??(quan)面??(mian)的??(de)時(shí)??(shi)空??(kong)轉(zhuǎn)??(zhuan)錄??(lu)組??(zu)資??(zi)源??(yuan)?，還??(hai)為??(wei)神??(shen)經(jīng)??(jing)發(fā)?(fa)育??(yu)的?(de)調(diào)??(tiao)控??(kong)機(jī)?(ji)制??(zhi)提?(ti)供??(gong)了??(le)新??(xin)的??(de)見??(jian)解??(jie)??。??　　非??(fei)編??(bian)碼??(ma)RNA??，尤??(you)其??(qi)是??(shi)長(zhǎng)??(chang)鏈??(lian)非??(fei)編??(bian)碼??(ma)RNA在??(zai)哺??(bu)乳??(ru)動(dòng)??(dong)物??(wu)大??(da)腦??(nao)的??(de)發(fā)??(fa)育??(yu)、成??(cheng)熟??(shu)和?(he)疾??(ji)病??(bing)中??(zhong)發(fā)??(fa)揮??(hui)著??(zhe)重??(zhong)要??(yao)作??(zuo)用??(yong)??。??作??(zuo)為??(wei)此??(ci)次??(ci)的??(de)研??(yan)究??(jiu)亮?(liang)點(diǎn)??(dian)之??(zhi)一??(yi)??，團(tuán)??(tuan)隊(duì)??(dui)首??(shou)次??(ci)整??(zheng)合??(he)了??(le)長(zhǎng)??(chang)鏈??(lian)非??(fei)編??(bian)碼?(ma)RNA的??(de)空??(kong)間??(jian)表??(biao)達(dá)?(da)數(shù)??(shu)據(jù)??(ju)??，發(fā)??(fa)現(xiàn)??(xian)長(zhǎng)??(chang)鏈??(lian)非??(fei)編??(bian)碼?(ma)RNA的??(de)表??(biao)達(dá)??(da)在??(zai)成??(cheng)年??(nian)小??(xiao)鼠??(shu)大?(da)腦??(nao)中??(zhong)具?(ju)有??(you)區(qū)?(qu)域?(yu)選??(xuan)擇??(ze)性??(xing)??，在??(zai)發(fā)?(fa)育??(yu)中??(zhong)的??(de)小??(xiao)鼠??(shu)大??(da)腦?(nao)內(nèi)??(nei)則??(ze)呈??(cheng)現(xiàn)??(xian)出??(chu)時(shí)?(shi)空??(kong)動(dòng)??(dong)態(tài)??(tai)性??(xing)??，為??(wei)神?(shen)經(jīng)??(jing)功??(gong)能??(neng)與??(yu)非??(fei)編??(bian)碼??(ma)RNA相??(xiang)關(guān)??(guan)性??(xing)的??(de)研??(yan)究??(jiu)奠??(dian)定??(ding)了??(le)基??(ji)礎(chǔ)??(chu)??。(完??(wan))。