三九養(yǎng)生堂記者 鄧肯·蓋伊 報道
精彩| 據(jù)??(ju)研??(yan)究?(jiu)團??(tuan)隊??(dui)介??(jie)紹??(shao)??，為?(wei)對??(dui)CRAQ進??(jin)行??(xing)性??(xing)能??(neng)測??(ce)試??(shi)和??(he)評??(ping)估??(gu)??，他??(ta)們??(men)以??(yi)人??(ren)類??(lei)參??(can)考??(kao)基??(ji)因??(yin)組??(zu)組??(zu)裝??(zhuang)為??(wei)基??(ji)礎(chǔ)??(chu)構(gòu)??(gou)建??(jian)一??(yi)個??(ge)模??(mo)擬??(ni)數(shù)??(shu)據(jù)??(ju)集??(ji)并??(bing)利??(li)用??(yong)CRAQ和??(he)目??(mu)前??(qian)廣??(guang)泛??(fan)使?(shi)用??(yong)的?(de)基??(ji)因??(yin)組??(zu)質(zhì)??(zhi)量??(liang)評?(ping)估?(gu)工??(gong)具??(ju)進??(jin)行??(xing)測??(ce)試??(shi)和??(he)比??(bi)較??(jiao)??，結(jié)??(jie)果??(guo)表??(biao)明??(ming)??，當??(dang)缺??(que)乏??(fa)完??(wan)美??(mei)參??(can)考??(kao)基??(ji)因??(yin)組??(zu)時??(shi)??，CRAQ表?(biao)現(xiàn)??(xian)最??(zui)佳??(jia)??，并??(bing)在??(zai)檢??(jian)測??(ce)雜??(za)合??(he)區(qū)?(qu)域??(yu)方??(fang)面??(mian)也??(ye)表??(biao)現(xiàn)??(xian)出??(chu)超??(chao)過??(guo)95%的??(de)召??(zhao)回?(hui)率??(lv)和??(he)精??(jing)確??(que)度??(du)??。??研??(yan)究??(jiu)團??(tuan)隊??(dui)還??(hai)通??(tong)過??(guo)對??(dui)一??(yi)個??(ge)真?(zhen)實??(shi)的??(de)果??(guo)蠅??(ying)雜??(za)交??(jiao)的??(de)基??(ji)因??(yin)組??(zu)數(shù)??(shu)據(jù)??(ju)集??(ji)進??(jin)行?(xing)分??(fen)析??(xi)??，發(fā)??(fa)現(xiàn)??(xian)CRAQ可?(ke)以??(yi)準??(zhun)確??(que)地??(di)將??(jiang)組??(zu)裝??(zhuang)錯??(cuo)誤??(wu)和??(he)雜??(za)合??(he)區(qū)??(qu)域?(yu)區(qū)??(qu)分??(fen)開??(kai)來??(lai)??，而??(er)其??(qi)他??(ta)工??(gong)具??(ju)則??(ze)無??(wu)法?(fa)檢??(jian)測??(ce)出??(chu)雜??(za)合??(he)區(qū)?(qu)域??(yu)??。(完??(wan)) 針??(zhen)對?(dui)這??(zhe)一??(yi)問??(wen)題??(ti)??，該??(gai)研??(yan)究??(jiu)團??(tuan)隊??(dui)研??(yan)發(fā)??(fa)的??(de)CRAQ通?(tong)過??(guo)將??(jiang)原?(yuan)始??(shi)測??(ce)序??(xu)序??(xu)列??(lie)比??(bi)對??(dui)到秘(dao)組??(zu)裝??(zhuang)的??(de)基??(ji)因??(yin)組??(zu)上??(shang)??，基??(ji)于??(yu)序??(xu)列??(lie)比??(bi)對??(dui)產(chǎn)??(chan)生??(sheng)的??(de)有??(you)效??(xiao)“剪?(jian)切?(qie)對??(dui)齊?(qi)”信??(xin)息??(xi)??，可?(ke)精??(jing)準??(zhun)地??(di)檢?(jian)測??(ce)基??(ji)因??(yin)組??(zu)中??(zhong)存??(cun)在??(zai)的??(de)組??(zu)裝??(zhuang)錯??(cuo)誤??(wu)??。??結(jié)??(jie)合??(he)長??(chang)讀??(du)長??(chang)測??(ce)序??(xu)片??(pian)段??(duan)和??(he)短??(duan)讀??(du)長??(chang)測??(ce)序??(xu)片??(pian)段??(duan)與??(yu)基??(ji)因??(yin)組??(zu)比??(bi)對??(dui)的?(de)特??(te)征?(zheng)??，CRAQ可??(ke)以?(yi)識??(shi)別??(bie)基??(ji)因??(yin)組??(zu)內(nèi)??(nei)小??(xiao)規(guī)?(gui)模??(mo)的??(de)區(qū)??(qu)域??(yu)組??(zu)裝??(zhuang)錯??(cuo)誤??(wu)和??(he)大??(da)范??(fan)圍??(wei)的??(de)結(jié)??(jie)構(gòu)??(gou)組??(zu)裝??(zhuang)錯??(cuo)誤??(wu)??，不??(bu)同?(tong)類??(lei)別??(bie)的??(de)錯??(cuo)誤??(wu)數(shù)??(shu)量??(liang)經(jīng)??(jing)過??(guo)統(tǒng)??(tong)計??(ji)和??(he)標??(biao)準??(zhun)化??(hua)處??(chu)理??(li)后??(hou)被??(bei)轉(zhuǎn)??(zhuan)化??(hua)為??(wei)兩??(liang)個??(ge)組??(zu)裝??(zhuang)質(zhì)??(zhi)量??(liang)評??(ping)估??(gu)指??(zhi)標??(biao)??，以??(yi)反??(fan)映??(ying)不??(bu)同??(tong)層??(ceng)面??(mian)的??(de)基??(ji)因??(yin)組??(zu)組??(zu)裝??(zhuang)質(zhì)??(zhi)量??(liang)??。
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