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學(xué)習(xí)快評(píng)丨qibao666888　　研??(yan)究??(jiu)團(tuán)??(tuan)隊(duì)??(dui)培??(pei)育?(yu)了??(le)具??(ju)有??(you)自??(zi)閉??(bi)癥?(zheng)樣??(yang)癥??(zheng)狀??(zhuang)的?(de)MEF2C缺??(que)陷??(xian)小??(xiao)鼠??(shu)??。??這??(zhe)些??(xie)小??(xiao)鼠??(shu)不??(bu)僅??(jin)表??(biao)現(xiàn)??(xian)出?(chu)嚴(yán)??(yan)重??(zhong)的??(de)社??(she)交??(jiao)障??(zhang)礙??(ai)?，在??(zai)水??(shui)迷??(mi)宮??(gong)測(cè)??(ce)試??(shi)中??(zhong)也??(ye)頻??(pin)頻??(pin)迷??(mi)失??(shi)方??(fang)向??(xiang)??。經(jīng)??(jing)過(guò)??(guo)8周??(zhou)使??(shi)用??(yong)BMS265246治??(zhi)療??(liao)?，這??(zhe)群??(qun)小??(xiao)鼠??(shu)腦??(nao)部??(bu)的??(de)炎??(yan)癥?(zheng)因??(yin)子??(zi)風(fēng)??(feng)暴??(bao)消??(xiao)退??(tui)?，開(kāi)??(kai)始??(shi)主??(zhu)動(dòng)??(dong)嗅??(xiu)探??(tan)同??(tong)伴??(ban)?，尋??(xun)找??(zhao)水?(shui)迷??(mi)宮??(gong)平??(ping)臺(tái)??(tai)的??(de)速??(su)度??(du)顯??(xian)著??(zhu)提??(ti)升??(sheng)??。實(shí)??(shi)驗(yàn)?(yan)顯??(xian)示??(shi)?，藥??(yao)物??(wu)對(duì)??(dui)小??(xiao)鼠??(shu)沒(méi)??(mei)有??(you)造??(zao)成?(cheng)體??(ti)重??(zhong)減??(jian)輕??(qing)、脫??(tuo)發(fā)??(fa)、血?(xue)液??(ye)學(xué)??(xue)毒??(du)性??(xing)等??(deng)損??(sun)傷??(shang)???！　”??(bei)京??(jing)時(shí)??(shi)間??(jian)3月??(yue)25日??(ri)??，清??(qing)華??(hua)大??(da)學(xué)??(xue)藥??(yao)學(xué)??(xue)院??(yuan)丁??(ding)勝??(sheng)教??(jiao)授??(shou)團(tuán)??(tuan)隊(duì)??(dui)在??(zai)國(guó)??(guo)際??(ji)頂??(ding)級(jí)?(ji)學(xué)??(xue)術(shù)??(shu)期??(qi)刊??(kan)《Immunity》發(fā)??(fa)表??(biao)突??(tu)破??(po)性??(xing)研??(yan)究??(jiu)??，首??(shou)次??(ci)揭??(jie)示??(shi)控??(kong)制??(zhi)小??(xiao)膠??(jiao)質(zhì)?(zhi)細(xì)??(xi)胞??(bao)“加??(jia)速??(su)—控??(kong)速??(su)”平??(ping)衡??(heng)的?(de)關(guān)?(guan)鍵??(jian)開(kāi)??(kai)關(guān)??(guan)??，并??(bing)成?(cheng)功??(gong)從??(cong)2400多??(duo)種??(zhong)化??(hua)合??(he)物??(wu)中??(zhong)篩??(shai)選??(xuan)出??(chu)能?(neng)精??(jing)準(zhǔn)??(zhun)修??(xiu)復(fù)??(fu)該??(gai)系??(xi)統(tǒng)??(tong)的??(de)藥??(yao)物??(wu)小??(xiao)分??(fen)子??(zi)BMS265246??。??在?(zai)動(dòng)??(dong)物?(wu)實(shí)??(shi)驗(yàn)?(yan)中??(zhong)??，這?(zhe)種?(zhong)新??(xin)型??(xing)CDK2抑??(yi)制??(zhi)劑??(ji)使??(shi)患??(huan)病??(bing)小?(xiao)鼠??(shu)的??(de)腦??(nao)部??(bu)炎??(yan)癥??(zheng)消??(xiao)退祝(tui)??，社??(she)交??(jiao)和??(he)記??(ji)憶??(yi)功??(gong)能??(neng)基??(ji)本??(ben)恢??(hui)復(fù)??(fu)正??(zheng)常??(chang)??。這??(zhe)項(xiàng)??(xiang)發(fā)??(fa)現(xiàn)??(xian)不??(bu)僅??(jin)為??(wei)學(xué)??(xue)界?(jie)深??(shen)入??(ru)理??(li)解??(jie)細(xì)??(xi)胞?(bao)周??(zhou)期??(qi)蛋??(dan)白??(bai)調(diào)??(tiao)控??(kong)非??(fei)分??(fen)裂??(lie)細(xì)??(xi)胞?(bao)功??(gong)能??(neng)提??(ti)供??(gong)了??(le)嶄??(zhan)新??(xin)的??(de)實(shí)??(shi)例??(li)??，更??(geng)為??(wei)治??(zhi)療??(liao)十??(shi)多?(duo)種?(zhong)神?(shen)經(jīng)??(jing)疾??(ji)病??(bing)提??(ti)供??(gong)了??(le)全??(quan)新??(xin)路??(lu)徑??(jing)??。。