三九養(yǎng)生堂記者 鄧肯·蓋伊 報道
精彩| 論??(lun)文??(wen)通??(tong)訊??(xun)作??(zuo)者??(zhe)焦??(jiao)遠(yuǎn)??(yuan)年??(nian)研?(yan)究??(jiu)員?(yuan)指??(zhi)出?(chu)?，高?(gao)質(zhì)??(zhi)量??(liang)的??(de)參??(can)考??(kao)基??(ji)因??(yin)組??(zu)序??(xu)列??(lie)對??(dui)于??(yu)基??(ji)因??(yin)注??(zhu)釋??(shi)和??(he)相??(xiang)關(guān)??(guan)功??(gong)能?(neng)研?(yan)究??(jiu)至??(zhi)關(guān)??(guan)重?(zhong)要??(yao)?，也??(ye)是?(shi)大??(da)規(guī)??(gui)模??(mo)比??(bi)較??(jiao)基??(ji)因??(yin)組?(zu)學(xué)?(xue)和??(he)表??(biao)觀??(guan)遺??(yi)傳??(chuan)調(diào)??(tiao)控??(kong)研??(yan)究??(jiu)的??(de)重??(zhong)要??(yao)前??(qian)提??(ti)??。??不??(bu)過??(guo)?，目??(mu)前??(qian)多??(duo)數(shù)??(shu)基??(ji)因??(yin)組??(zu)序??(xu)列??(lie)中?(zhong)仍??(reng)然??(ran)存??(cun)在??(zai)一?(yi)些?(xie)組??(zu)裝??(zhuang)錯??(cuo)誤??(wu)?，給??(gei)相??(xiang)關(guān)??(guan)研??(yan)究??(jiu)帶??(dai)來??(lai)一??(yi)定??(ding)程??(cheng)度??(du)影??(ying)響??(xiang)??。而??(er)精??(jing)準(zhǔn)??(zhun)區(qū)??(qu)分??(fen)和??(he)鑒??(jian)定??(ding)高??(gao)質(zhì)??(zhi)量??(liang)與??(yu)低??(di)質(zhì)??(zhi)量??(liang)的??(de)基??(ji)因??(yin)組??(zu)序??(xu)列??(lie)?，不??(bu)僅??(jin)可??(ke)以??(yi)為??(wei)基??(ji)因??(yin)組??(zu)組?(zu)裝??(zhuang)質(zhì)?(zhi)量??(liang)提??(ti)供??(gong)評??(ping)估??(gu)依??(yi)據(jù)??(ju)和??(he)進(jìn)??(jin)一??(yi)步??(bu)改??(gai)進(jìn)??(jin)提??(ti)供??(gong)靶??(ba)點??(dian)?，也?(ye)可??(ke)以??(yi)為??(wei)后??(hou)期??(qi)比??(bi)較??(jiao)基??(ji)因??(yin)組??(zu)和??(he)功??(gong)能??(neng)研??(yan)究??(jiu)位??(wei)點??(dian)提??(ti)供??(gong)基??(ji)因??(yin)組??(zu)序??(xu)列??(lie)質(zhì)??(zhi)量??(liang)認(rèn)??(ren)證??(zheng)??。當(dāng)??(dang)前??(qian)?，雖??(sui)然??(ran)已??(yi)有??(you)一??(yi)些??(xie)基??(ji)因??(yin)組??(zu)組??(zu)裝??(zhuang)質(zhì)??(zhi)量??(liang)評??(ping)估??(gu)的??(de)方?(fang)法??(fa)和??(he)指??(zhi)標(biāo)??(biao)?，但??(dan)其??(qi)大??(da)多??(duo)僅??(jin)提??(ti)供??(gong)一?(yi)個??(ge)總??(zong)體??(ti)的?(de)評??(ping)估??(gu)值??(zhi)?，沒?(mei)有??(you)針??(zhen)對??(dui)特??(te)定??(ding)區(qū)?(qu)域??(yu)或??(huo)堿??(jian)基??(ji)的??(de)評??(ping)估??(gu)信?(xin)息??(xi)??。 據(jù)??(ju)研??(yan)究??(jiu)團(tuán)??(tuan)隊??(dui)介??(jie)紹??(shao)??，為?(wei)對??(dui)CRAQ進(jìn)??(jin)行??(xing)性??(xing)能??(neng)測??(ce)試??(shi)和??(he)評??(ping)估?(gu)??，他??(ta)們??(men)以??(yi)人??(ren)類??(lei)參??(can)考??(kao)基??(ji)因?(yin)組??(zu)組??(zu)裝??(zhuang)為??(wei)基??(ji)礎(chǔ)??(chu)構(gòu)??(gou)建??(jian)一??(yi)個?(ge)模??(mo)擬??(ni)數(shù)??(shu)據(jù)??(ju)集??(ji)并??(bing)利??(li)用??(yong)CRAQ和??(he)目??(mu)前??(qian)廣??(guang)泛?(fan)使??(shi)用??(yong)的??(de)基??(ji)因??(yin)組?(zu)質(zhì)??(zhi)量??(liang)評??(ping)估??(gu)工?(gong)具??(ju)進(jìn)??(jin)行??(xing)測??(ce)試??(shi)和??(he)比??(bi)較??(jiao)??，結(jié)??(jie)果??(guo)表??(biao)明??(ming)??，當(dāng)??(dang)缺??(que)乏?(fa)完??(wan)美??(mei)參??(can)考??(kao)基??(ji)因??(yin)組??(zu)時??(shi)??，CRAQ表??(biao)現(xiàn)??(xian)最??(zui)佳??(jia)??，并??(bing)在??(zai)檢??(jian)測??(ce)雜??(za)合??(he)區(qū)??(qu)域??(yu)方??(fang)面?(mian)也??(ye)表??(biao)現(xiàn)?(xian)出?(chu)超??(chao)過??(guo)95%的??(de)召??(zhao)回?(hui)率??(lv)和??(he)精??(jing)確??(que)度?(du)??。??研??(yan)究??(jiu)團(tuán)?(tuan)隊??(dui)還??(hai)通??(tong)過??(guo)對??(dui)一?(yi)個??(ge)真??(zhen)實??(shi)的??(de)果??(guo)蠅??(ying)雜??(za)交??(jiao)的??(de)基?(ji)因??(yin)組?(zu)數(shù)?(shu)據(jù)??(ju)集?(ji)進(jìn)??(jin)行??(xing)分?(fen)析??(xi)??，發(fā)??(fa)現(xiàn)??(xian)CRAQ可??(ke)以??(yi)準(zhǔn)?(zhun)確??(que)地??(di)將??(jiang)組??(zu)裝??(zhuang)錯??(cuo)誤??(wu)和??(he)雜??(za)合??(he)區(qū)??(qu)域??(yu)區(qū)??(qu)分??(fen)開?(kai)來?(lai)??，而??(er)其??(qi)他??(ta)工??(gong)具??(ju)則??(ze)無?(wu)法??(fa)檢??(jian)測??(ce)出??(chu)雜??(za)合?(he)區(qū)??(qu)域??(yu)??。(完??(wan))
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責(zé)編：楊之光
審核：吉尼
責(zé)編：呂程平