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學(xué)習(xí)快評丨qibao666888　　正??(zheng)常??(chang)小??(xiao)膠?(jiao)質(zhì)??(zhi)細(xì)?(xi)胞??(bao)像??(xiang)紀(jì)?(ji)律??(lv)嚴(yán)??(yan)明??(ming)的??(de)“衛(wèi)??(wei)兵??(bing)”??，保??(bao)障??(zhang)了??(le)大??(da)腦??(nao)中??(zhong)正??(zheng)常??(chang)的??(de)神??(shen)經(jīng)??(jing)活?(huo)動??(dong)??。??MEF2C缺??(que)失??(shi)的??(de)細(xì)??(xi)胞??(bao)則??(ze)會??(hui)轉(zhuǎn)?(zhuan)變??(bian)為??(wei)“暴?(bao)徒?(tu)”??，對??(dui)神??(shen)經(jīng)??(jing)系??(xi)統(tǒng)??(tong)造??(zao)成??(cheng)巨??(ju)大?(da)破??(po)壞??(huai)??，分??(fen)泌??(mi)的??(de)炎??(yan)癥?(zheng)物??(wu)質(zhì)??(zhi)在??(zai)正??(zheng)常??(chang)水??(shui)平??(ping)的??(de)3倍??(bei)以??(yi)上??(shang)??，這??(zhe)復(fù)??(fu)現(xiàn)?(xian)了??(le)自??(zi)閉??(bi)癥??(zheng)患??(huan)者??(zhe)腦??(nao)部??(bu)的??(de)典??(dian)型??(xing)病?(bing)理??(li)特??(te)征??(zheng)???！　”??(bei)京??(jing)時??(shi)間??(jian)3月??(yue)25日?(ri)??，清??(qing)華??(hua)大??(da)學(xué)?(xue)藥??(yao)學(xué)??(xue)院??(yuan)丁??(ding)勝??(sheng)教??(jiao)授??(shou)團??(tuan)隊??(dui)在??(zai)國??(guo)際??(ji)頂秘(ding)級??(ji)學(xué)??(xue)術(shù)??(shu)期??(qi)刊??(kan)《Immunity》發(fā)??(fa)表??(biao)突??(tu)破??(po)性??(xing)研??(yan)究??(jiu)??，首??(shou)次??(ci)揭??(jie)示??(shi)控?(kong)制??(zhi)小?(xiao)膠??(jiao)質(zhì)??(zhi)細(xì)??(xi)胞??(bao)“加??(jia)速??(su)—控??(kong)速??(su)”平??(ping)衡??(heng)的??(de)關(guān)??(guan)鍵??(jian)開??(kai)關(guān)??(guan)??，并??(bing)成?(cheng)功??(gong)從??(cong)2400多??(duo)種??(zhong)化??(hua)合??(he)物??(wu)中??(zhong)篩??(shai)選??(xuan)出??(chu)能??(neng)精??(jing)準(zhǔn)??(zhun)修??(xiu)復(fù)??(fu)該??(gai)系??(xi)統(tǒng)??(tong)的??(de)藥??(yao)物??(wu)小??(xiao)分?(fen)子??(zi)BMS265246??。??在??(zai)動??(dong)物??(wu)實??(shi)驗??(yan)中??(zhong)??，這??(zhe)種??(zhong)新??(xin)型??(xing)CDK2抑??(yi)制??(zhi)劑??(ji)使??(shi)患??(huan)病??(bing)小??(xiao)鼠?(shu)的??(de)腦??(nao)部??(bu)炎??(yan)癥??(zheng)消??(xiao)退??(tui)??，社??(she)交??(jiao)和??(he)記?(ji)憶??(yi)功??(gong)能??(neng)基??(ji)本??(ben)恢??(hui)復(fù)??(fu)正??(zheng)常??(chang)??。這??(zhe)項??(xiang)發(fā)??(fa)現(xiàn)??(xian)不??(bu)僅??(jin)為??(wei)學(xué)??(xue)界??(jie)深??(shen)入??(ru)理??(li)解??(jie)細(xì)??(xi)胞??(bao)周??(zhou)期??(qi)蛋??(dan)白??(bai)調(diào)??(tiao)控??(kong)非??(fei)分??(fen)裂??(lie)細(xì)??(xi)胞??(bao)功??(gong)能??(neng)提??(ti)供?(gong)了??(le)嶄?(zhan)新??(xin)的?(de)實??(shi)例??(li)??，更??(geng)為??(wei)治??(zhi)療??(liao)十?(shi)多??(duo)種??(zhong)神?(shen)經(jīng)??(jing)疾??(ji)病??(bing)提??(ti)供?(gong)了??(le)全?(quan)新??(xin)路??(lu)徑??(jing)??。。