三九養(yǎng)生堂記者 鄧肯·蓋伊 報(bào)道
精彩| 論??(lun)文??(wen)通??(tong)訊??(xun)作??(zuo)者??(zhe)焦??(jiao)遠(yuǎn)?(yuan)年??(nian)研??(yan)究??(jiu)員??(yuan)指??(zhi)出??(chu)??，高??(gao)質(zhì)??(zhi)量??(liang)的??(de)參??(can)考??(kao)基??(ji)因??(yin)組??(zu)序??(xu)列??(lie)對(duì)??(dui)于??(yu)基??(ji)因??(yin)注??(zhu)釋??(shi)和??(he)相??(xiang)關(guān)??(guan)功?(gong)能??(neng)研?(yan)究??(jiu)至??(zhi)關(guān)??(guan)重??(zhong)要?(yao)??，也??(ye)是??(shi)大??(da)規(guī)??(gui)模??(mo)比??(bi)較??(jiao)基??(ji)因??(yin)組??(zu)學(xué)??(xue)和??(he)表??(biao)觀??(guan)遺??(yi)傳??(chuan)調(diào)??(tiao)控??(kong)研??(yan)究??(jiu)的??(de)重??(zhong)要??(yao)前??(qian)提??(ti)??。??不??(bu)過??(guo)??，目??(mu)前??(qian)多??(duo)數(shù)??(shu)基??(ji)因??(yin)組?(zu)序??(xu)列??(lie)中??(zhong)仍??(reng)然??(ran)存??(cun)在??(zai)一??(yi)些??(xie)組??(zu)裝??(zhuang)錯(cuò)??(cuo)誤??(wu)??，給??(gei)相??(xiang)關(guān)??(guan)研??(yan)究??(jiu)帶??(dai)來??(lai)一??(yi)定??(ding)程??(cheng)度?(du)影??(ying)響??(xiang)??。而??(er)精??(jing)準(zhǔn)??(zhun)區(qū)??(qu)分??(fen)和??(he)鑒??(jian)定??(ding)高??(gao)質(zhì)??(zhi)量??(liang)與??(yu)低??(di)質(zhì)??(zhi)量??(liang)的??(de)基??(ji)因??(yin)組??(zu)序??(xu)列??(lie)??，不??(bu)僅??(jin)可??(ke)以??(yi)為??(wei)基??(ji)因??(yin)組??(zu)組??(zu)裝??(zhuang)質(zhì)??(zhi)量??(liang)提??(ti)供??(gong)評(píng)??(ping)估??(gu)依??(yi)據(jù)??(ju)和??(he)進(jìn)??(jin)一??(yi)步??(bu)改??(gai)進(jìn)??(jin)提??(ti)供??(gong)靶??(ba)點(diǎn)??(dian)??，也??(ye)可??(ke)以??(yi)為??(wei)后?(hou)期??(qi)比?(bi)較??(jiao)基??(ji)因??(yin)組??(zu)和?(he)功??(gong)能??(neng)研??(yan)究??(jiu)位??(wei)點(diǎn)??(dian)提??(ti)供??(gong)基??(ji)因??(yin)組??(zu)序??(xu)列?(lie)質(zhì)??(zhi)量??(liang)認(rèn)??(ren)證??(zheng)??。當(dāng)??(dang)前??(qian)??，雖??(sui)然??(ran)已?(yi)有??(you)一??(yi)些?(xie)基??(ji)因??(yin)組??(zu)組??(zu)裝??(zhuang)質(zhì)??(zhi)量??(liang)評(píng)??(ping)估??(gu)的??(de)方??(fang)法??(fa)和??(he)指??(zhi)標(biāo)??(biao)??，但??(dan)其??(qi)大??(da)多??(duo)僅??(jin)提??(ti)供??(gong)一?(yi)個(gè)??(ge)總??(zong)體??(ti)的??(de)評(píng)??(ping)估??(gu)值??(zhi)??，沒?(mei)有??(you)針?(zhen)對(duì)?(dui)特??(te)定??(ding)區(qū)??(qu)域??(yu)或??(huo)堿??(jian)基??(ji)的??(de)評(píng)??(ping)估??(gu)信??(xin)息??(xi)???！ ♂??(zhen)對(duì)??(dui)這??(zhe)一??(yi)問??(wen)題??(ti)??，該??(gai)研??(yan)究??(jiu)團(tuán)??(tuan)隊(duì)??(dui)研??(yan)發(fā)??(fa)的??(de)CRAQ通??(tong)過??(guo)將??(jiang)原??(yuan)始??(shi)測(cè)??(ce)序??(xu)序??(xu)列??(lie)比??(bi)對(duì)??(dui)到?(dao)組?(zu)裝??(zhuang)的??(de)基?(ji)因??(yin)組??(zu)上??(shang)??，基??(ji)于??(yu)序??(xu)列??(lie)比??(bi)對(duì)??(dui)產(chǎn)??(chan)生??(sheng)的??(de)有??(you)效??(xiao)“剪??(jian)切??(qie)對(duì)??(dui)齊??(qi)”信??(xin)息??(xi)??，可??(ke)精秘(jing)準(zhǔn)??(zhun)地?(di)檢??(jian)測(cè)??(ce)基??(ji)因??(yin)組??(zu)中??(zhong)存??(cun)在??(zai)的??(de)組??(zu)裝??(zhuang)錯(cuò)??(cuo)誤??(wu)??。??結(jié)??(jie)合??(he)長(zhǎng)??(chang)讀??(du)長(zhǎng)??(chang)測(cè)??(ce)序??(xu)片??(pian)段??(duan)和??(he)短??(duan)讀??(du)長(zhǎng)??(chang)測(cè)??(ce)序?(xu)片??(pian)段??(duan)與??(yu)基??(ji)因??(yin)組??(zu)比??(bi)對(duì)??(dui)的??(de)特??(te)征??(zheng)??，CRAQ可??(ke)以??(yi)識(shí)??(shi)別??(bie)基??(ji)因??(yin)組??(zu)內(nèi)??(nei)小?(xiao)規(guī)??(gui)模??(mo)的?(de)區(qū)??(qu)域??(yu)組??(zu)裝??(zhuang)錯(cuò)??(cuo)誤??(wu)和??(he)大??(da)范??(fan)圍??(wei)的??(de)結(jié)??(jie)構(gòu)??(gou)組??(zu)裝??(zhuang)錯(cuò)??(cuo)誤??(wu)??，不??(bu)同??(tong)類??(lei)別??(bie)的??(de)錯(cuò)?(cuo)誤??(wu)數(shù)??(shu)量??(liang)經(jīng)??(jing)過??(guo)統(tǒng)??(tong)計(jì)??(ji)和??(he)標(biāo)??(biao)準(zhǔn)??(zhun)化??(hua)處??(chu)理?(li)后??(hou)被??(bei)轉(zhuǎn)??(zhuan)化??(hua)為??(wei)兩??(liang)個(gè)??(ge)組??(zu)裝??(zhuang)質(zhì)??(zhi)量??(liang)評(píng)??(ping)估??(gu)指??(zhi)標(biāo)??(biao)??，以??(yi)反?(fan)映??(ying)不??(bu)同??(tong)層??(ceng)面??(mian)的??(de)基??(ji)因??(yin)組??(zu)組??(zu)裝??(zhuang)質(zhì)??(zhi)量??(liang)??。
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