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學習快評丨qibao666888　　蛋??(dan)白??(bai)質(zhì)??(zhi)是??(shi)由??(you)20種??(zhong)氨??(an)基??(ji)酸??(suan)組??(zu)成??(cheng)的??(de)一?(yi)條?(tiao)高??(gao)分??(fen)子??(zi)鏈??(lian)??，這??(zhe)個??(ge)高??(gao)分??(fen)子??(zi)鏈?(lian)會??(hui)扭??(niu)曲??(qu)并??(bing)折??(zhe)疊??(die)成??(cheng)獨?(du)特??(te)的??(de)三??(san)維??(wei)結??(jie)構??(gou)??，正??(zheng)是??(shi)這??(zhe)種??(zhong)獨?(du)特??(te)結??(jie)構??(gou)賦??(fu)予??(yu)了??(le)特??(te)定??(ding)蛋??(dan)白??(bai)質(zhì)??(zhi)的?(de)生??(sheng)物??(wu)功??(gong)能??(neng)??。??要??(yao)設??(she)計??(ji)出?(chu)一??(yi)款??(kuan)成?(cheng)功??(gong)的??(de)蛋??(dan)白??(bai)質(zhì)??(zhi)產(chǎn)?(chan)品??(pin)??，不??(bu)能??(neng)只??(zhi)關??(guan)注??(zhu)它??(ta)的??(de)三??(san)維??(wei)結??(jie)構??(gou)??，而??(er)是??(shi)要??(yao)能??(neng)成??(cheng)功??(gong)預??(yu)測??(ce)和??(he)設??(she)計??(ji)它??(ta)的??(de)功??(gong)能??(neng)??。洪??(hong)亮??(liang)團?(tuan)隊??(dui)直??(zhi)接??(jie)瞄??(miao)準?(zhun)“功??(gong)能??(neng)預??(yu)測??(ce)”這?(zhe)一??(yi)終??(zhong)極??(ji)目??(mu)標??(biao)??，將??(jiang)復??(fu)雜??(za)的??(de)蛋??(dan)白??(bai)質(zhì)?(zhi)設??(she)計??(ji)變??(bian)成?(cheng)以?(yi)需??(xu)求?(qiu)為??(wei)導??(dao)向?(xiang)??，配??(pei)合??(he)少??(shao)量??(liang)實??(shi)驗?(yan)輸??(shu)出??(chu)結??(jie)果??(guo)的?(de)簡??(jian)單??(dan)過??(guo)程??(cheng)???！　　拔??(wo)們??(men)訓??(xun)練??(lian)了??(le)Venus(啟??(qi)明?(ming)星??(xing))系??(xi)列??(lie)模??(mo)型??(xing)??，與?(yu)DeepMind團??(tuan)隊?(dui)的??(de)AlphaFold預??(yu)測??(ce)蛋??(dan)白??(bai)質(zhì)??(zhi)結??(jie)構??(gou)不??(bu)同??(tong)??，這??(zhe)個?(ge)模??(mo)型??(xing)學??(xue)習??(xi)自??(zi)然??(ran)界??(jie)蛋??(dan)白??(bai)質(zhì)??(zhi)序??(xu)列??(lie)的??(de)組??(zu)織?(zhi)規(guī)??(gui)則??(ze)以??(yi)及?(ji)它??(ta)與??(yu)功??(gong)能??(neng)之??(zhi)間??(jian)的??(de)關?(guan)系??(xi)??，其??(qi)預??(yu)測??(ce)蛋??(dan)白??(bai)質(zhì)??(zhi)突??(tu)變??(bian)功??(gong)能??(neng)的??(de)精??(jing)度??(du)位??(wei)居??(ju)行??(xing)業(yè)??(ye)榜??(bang)單??(dan)之?(zhi)首??(shou)??。??”洪??(hong)亮?(liang)說??(shuo)??，Venus系??(xi)列??(lie)模??(mo)型??(xing)具??(ju)備??(bei)兩??(liang)大??(da)核??(he)心??(xin)功??(gong)能??(neng)：“AI定??(ding)向??(xiang)進??(jin)化??(hua)”與??(yu)“AI挖??(wa)酶??(mei)”??。這??(zhe)些??(xie)超??(chao)常?(chang)規(guī)??(gui)功?(gong)能??(neng)的??(de)蛋??(dan)白??(bai)質(zhì)??(zhi)在??(zai)生??(sheng)物?(wu)技??(ji)術??(shu)、醫(yī)??(yi)藥??(yao)研??(yan)發(fā)??(fa)和??(he)工?(gong)業(yè)??(ye)生??(sheng)產(chǎn)??(chan)中??(zhong)具??(ju)有??(you)巨??(ju)大??(da)的?(de)應??(ying)用??(yong)潛??(qian)力??(li)??，能??(neng)夠??(gou)為??(wei)相??(xiang)關??(guan)領?(ling)域?(yu)帶??(dai)來??(lai)創(chuàng)??(chuang)新??(xin)和??(he)突??(tu)破??(po)??。。